MTT-S Virtual Successes [President's Column]

Reduction of MTT by glutathione S-transferase.

The reduction of the tetrazolium salt 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide (MTT) to a blue formazan product is widely used for assaying cell survival and proliferation. The reduction reaction is catalyzed by dehydrogenases localized in the mitochondria of viable cells. As part of an analysis of the ability of glutathione S-transferase (GST) enzymes to protect cells from...

Presidents, Vice Presidents, and Death: Closing the Constitution's Succession Gap

Exploring Chemistry Using Virtual Instrumentation - Challenges and Successes

During the last decades the humanity realized the great problems that changed the environment equilibrium. The scientists from all over the world are working now to understand the nature and to prevent the natural disasters. But, what we are doing for training of these scientists? Have we enough resources and attractive methods for teaching Sciences to students and attract them to study the Sci...

Underwriting the presidents.

The United States has had 43 presidents. We examined whether they survive significantly longer or shorter than their contemporaries. We found that survival was better for presidents elected in the 1789-1841 and 1933-2001 periods (SMRs of 0.7 and 0.6, respectively), but worse for those elected in 1845-1929 (SMR = 2.9). We also found increased mortality during the years lived in office (SMR = 1.4...

Presidents who value science.

www.sciencemag.org SCIENCE VOL 323 13 FEBRUARY 2009 843 COVER An image of Mare Moscoviense on the lunar farside, taken by the Terrain Camera aboard the SELENE (Kaguya) spacecraft on 17 January 2008. Crater frequency distributions derived from such images yield ages of about 2.5 billion years for several volcanic deposits in this mare, indicating that volcanism on the lunar farside lasted about ...